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CBG - The Mother of Cannabinoids


What is CBG?

CBG, also known as cannabigerol, is a lesser-known cannabinoid present in the hemp plant. Because it’s a precursor compound to other cannabinoids, CBG is nicknamed the “mother” or “stem cell” cannabinoid. And like other cannabinoids, it interacts with the body’s endocannabinoid system to affect a variety of physiological and cognitive processes.

Scientists have known about CBG for a long time, but it’s only recently stepped into the spotlight, and may soon become the next big thing in the world of hemp and cannabis medicine. Expect to see more CBG products in the near future, possibly becoming as popular as CBD is today.

A CBG flower is a hemp or cannabis bud that has been specifically bred to contain high concentrations of CBG. CBG flower is non-intoxicating and naturally contains very low levels of THC, which means that you can’t get high from consuming it.

CBG Benefits and Effects

CBG is known to enhance mood by stimulating the production of anandamide, which is a native cannabinoid known as the “bliss” chemical. This results in a feeling of wellbeing.

Because of these effects, CBG can also be used to alleviate anxiety, an effect that is magnified by the way that CBG inhibits GABA uptake, which encourages increased levels of serotonin and GABA in the brain. Interestingly, this is similar to how many anti-anxiety medications are supposed to work.

Early studies on CBG’s potential medical applications found this cannabinoid to be effective in treating chronic pain and inflammation, which also gives it certain neuroprotective properties which may be able to help conditions such as Huntington’s Disease.

Interestingly, CBG is also known to be antibacterial and antifungal. Further research is needed, but it may become useful for combating antibiotic-resistant bacterial infections such as MRSA.

Hemp Strains High in CBG

Most hemp strains contain less than 1% CBG. That’s why CBG is the most expensive cannabinoid to extract from regular strains, and why cannabis growers are hard at work to develop new strains that produce more CBG. Here are a few worth noting:

  • White Whale
  • Magic Jordan
  • Destroyer
  • Mickey Kush
  • Allen Wrench
  • Bleu Berries
  • Eldorado
  • Matterhorn
  • Jack Frost
  • White
  • Super Glue
  • Lemon Cream Diesel
  • CBG Flower


CBD vs CBG

CBD and CBG may sound similar, and while they are both cannabinoids, they have significant differences in the plants themselves, as well as how they affect the human body.

CBD is one of the most plentiful cannabinoids found in Cannabis plants. CBG is one of the least plentiful — that is because CBG acts like a “stem cell” molecule for the creation of other cannabinoids. As the plant matures, the amount of CBG present dwindles as it is converted into other compounds.

Because CBD is so abundant in Cannabis plants, it’s fairly easy to extract in meaningful quantities. However, because CBG is so rare, it’s much more difficult to extract for concentration in products like therapeutic oils.

In the human body, CBD interacts indirectly with the endocannabinoid system by stimulating the FAAH enzyme, which is responsible for the production of endocannabinoids in the body. Meanwhile, CBG directly interacts with the endocannabinoid system through CB1, CB2, and 5-HT1A receptors.

The effects of CBD and CBG overlap in many areas, but while CBD is known to have mental health, seizure prevention, and pain relief benefits, CBG is speculated to be better for acne spot treatments, bladder dysfunction, and IBS treatment.


What is CBG Hemp Flower?

CBG hemp flower is a Cannabis strain that has been specifically bred for a higher CBG content through genetic manipulation and crossbreeding. CBG hemp flowers are also harvested at a different point in the plant’s flowering cycle. The recommended period for CBG harvesting and extraction is around 6 weeks.


CBG Hemp Flower Uses

Cannabigerol (CBG) is currently being studied for its potential pharmacological properties, but so far it hasn't entered any clinical trials. However, early studies are linking the compound to several potential therapeutic uses:

Glaucoma: CBG may treat glaucoma and relieve intraocular pressure. This is significant because CBD on its own does not help with glaucoma, but THC has shown beneficial effects. CBG may be able to help glaucoma patients relieve their symptoms in a more legal way.

Antibacterial properties: CBG may be able to help combat antibiotic-resistant bacteria such as MRSA (Methicillin-resistant Staphylococcus aureus). This bacterial infection is known to be particularly life-threatening, and CBG may be the solution to this problem.

GABA reuptake inhibition: GABA uptake inhibitor medications are used to manage insomnia, anxiety, seizures, and chronic pain. CBG may have similar properties that can promote muscle relaxation, tension relief, and general calming without the need for these medications.

IBS and colitis: CBG may be able to provide relief for those who suffer from abdominal pain, joint pain, cramping, diarrhea, poor appetite, weight loss, and nausea related irritable bowel syndrome and colitis.

Skin conditions: CBG may be able to help treat and resolve inflammatory skin conditions such as acne, eczema, and psoriasis.

Neurodegenerative diseases: Early studies suggest that CBG may be able to treat neurodegenerative diseases such as Huntington’s due to its neuroprotective properties.

Cancer: CBG may have properties that inhibit the growth of certain cancer cells, slowing and possibly even inhibiting tumor growth. It also has certain appetite stimulating properties, which is helpful for chemotherapy patients.


How Does CBG Hemp Flower Work?

CBG hemp flowers, when consumed via inhalation or ingestion, provide CBG and CBD to interact with the endocannabinoid system both directly and indirectly. For THC users, consumption of CBG hemp flower tends to help buffer THC’s psychoactive properties and can alleviate feelings of paranoia.


How Should I Use CBG Hemp Flower?

CBG hemp flower can be smoked, vaped, or eaten.

Smoking

Smoking is a less-popular method of consuming hemp flowers, as smoking tends to produce a stronger smell, burns the nutrients, and may lead to the inhalation of ash and harmful compounds produced by combustion. That being said, there’s no link between smoking hemp flower joints and the development of lung cancer or chronic obstructive pulmonary disease (COPD).

Dry herb vape

Dry herb vape is the most popular form of hemp flower consumption, as it’s widely considered to be safer, as well as the most effective. When hemp flowers are consumed via dry herb vaporization, you are able to activate and consume the full scope of therapeutic elements. Users also report better flavor as well.

When smoking or vaping hemp flowers, do not hold the smoke in your lungs longer than normal. This does not maximize the benefits, contrary to popular belief, and only strains the lungs.

Edibles

You can also create your own cannabinoid-infused cannabutter from hemp flowers, which then can be used in a variety of culinary applications. Keep in mind that in order to activate the beneficial effects of the cannabinoids, the hemp flower needs to be heated. For best results, break the flower into small pieces, place on a baking tray, and bake for 1 hour at 110-120°F.


What is the Ideal Ratio of CBG and CBD?

When cannabinoids are consumed together, it creates an entourage effect. As it turns out, cannabinoids work best when they are together, and the benefits from each compound can be maximized. This is why it’s arguably better to consume whole hemp flower rather than using an isolate.

There is no official “ideal” ratio, but some argue that the ideal ratio between CBG and CBD is 1:1. As long as both are present in significant amounts, you will feel benefits.


Does CBG Hemp Flower Have Any Side Effects?

Cannabigerol (CBG) does not have any known adverse effects.


What Makes CBG The Mother of Cannabinoids?

All cannabinoids begin as cannabigerol, which is why it’s known as the “Mother” of all cannabinoids, or the “stem cell” cannabinoid. As a Cannabis plant matures, CBG gets gradually broken down and converted into the THC, CBD, and CBC that we know.